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Combination formulations that include amylin analogs with other incretins like GLP-1, such as cagrisema, are currently being assessed for the treatment of obesity and metabolic disorders
Aside from insulin, adrenal hormones like aldosterone and anti-diuretic hormone (ADH) also play a role in mineral and fluid retention
By inhibiting calcium influx, exendin-4 reduces the calcium overload, which leads to apoptosis and excitation-induced neurotoxicity in RGCs, promoting RGC survival and function in DR (Wang et al., 2023)
[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Zheng J., Xiao K.L., Chen L., Wu C., Hu X., Zeng T., Chen X.Q., Li W.J., Deng X., Li H., et al
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